NASDAQ: IONS - Ionis Pharmaceuticals

Yield per half year: -20.81%
Dividend yield: 0.00%
Sector: Healthcare

Share chart Ionis Pharmaceuticals

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About Ionis Pharmaceuticals

Ionis Pharmaceuticals - биотехнологическая компания, базирующаяся в Карлсбаде, Калифорния, которая специализируется на открытии и разработке терапевтических средств, нацеленных на РНК. У компании есть 3 коммерчески одобренных препарата: Спинраза (Нусинерсен), Тегседи (Инотерсен) и WAYLIVRA, а также 4 препарата в основных исследованиях: томинерсен от болезни Хантингтона, тоферсен от SOD1-ALS, AKCEA-APO (a) -LRx от сердечно-сосудистых заболеваний. и AKCEA-TTR-LRx для всех форм амилоидоза TTR. До декабря 2015 года компания носила название Isis Pharmaceuticals.

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Компания была основана в 1989 году как Isis Pharmaceuticals Стэнли Т. Крук, бывшим руководителем отдела исследований GlaxoSmithKline, с целью коммерциализации антисмысловой терапии.
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IPO date 1991-05-17
ISIN US4622221004
Industry Biotechnology
Sector Health Care
Валюта usd
Валюта отчета usd
Див.доход ао 3.16
Дивиденд ао 0.66
Сайт http://www.ionispharma.com
Цена ао 33.41
Change price per day: 0% (33.41)
Change price per week: -2.85% (34.39)
Change price per month: +5.79% (31.58)
Change price per 3 month: -9.73% (37.01)
Change price per half year: -20.81% (42.19)
Change price per year: -20.79% (42.18)
Change price per 3 year: -19.08% (41.29)
Change price per 5 year: -31.79% (48.98)
Change price per 10 year: -23.86% (43.88)
Change price per year to date: -8.54% (36.53)
All parameters

Underestimation

Title Value Grade
P/S 7.4 1
P/BV 8.87 1
P/E 122.59 1
EV/EBITDA -13.44 0
Total: 3.5

Efficiency

Title Value Grade
ROA, % -15.15 0
ROE, % -93.1 0
Total: 0

Dividends

Title Value Grade
Div yield, % 0 0
DSI 0.625 6.25
Total: 2.23

Debt

Title Value Grade
Debt/EBITDA -2.96 10
Total: 8

Growth impulse

Title Value Grade
Yield Revenue, % -3.27 0
Yield Ebitda, % 176.21 10
Yield EPS, % -13.01 0
Total: 4
More

Transaction date Date of disclosure Insider Type Price Volume Quantity Share before, % Share after, % Document
04.02.2025 06.02.2025 Monia Brett P
Chief Executive Officer		 Sale 31.65 1 229 380 38843 0 -0.03 link
04.02.2025 06.02.2025 O'NEIL PATRICK R.
EVP CLO & General Counsel		 Sale 31.62 194 937 6165 0 0 link
16.01.2025 17.01.2025 Baroldi Joseph
EVP, Chief Business Officer		 Sale 32.7 33 648 1029 0 0 link
16.01.2025 17.01.2025 Baroldi Joseph
EVP, Chief Business Officer		 Sale 32.7 111 213 3401 0 0 link
16.01.2025 17.01.2025 BENNETT C FRANK
EVP, Chief Scientific Officer		 Sale 32.9 222 141 6752 0 0 link
16.01.2025 16.01.2025 Baroldi Joseph
Officer		 Purchase 32.7 111 213 3401 0 0 link
16.01.2025 16.01.2025 BENNETT C FRANK
Officer		 Purchase 32.7 220 790 6752 0 0 link
16.01.2025 16.01.2025 Birchler Brian
Officer		 Purchase 32.7 176 580 5400 0 0 link
16.01.2025 16.01.2025 Devers Shannon L.
Officer		 Purchase 32.7 139 531 4267 0 0 link
16.01.2025 16.01.2025 Geary Richard S
Officer		 Purchase 32.7 231 254 7072 0 0 link
16.01.2025 16.01.2025 HOUGEN ELIZABETH L
Officer		 Purchase 32.7 290 049 8870 0 0.01 link
16.01.2025 16.01.2025 Monia Brett P
Officer		 Purchase 32.7 1 093 650 33445 0 0.02 link
16.01.2025 16.01.2025 O'NEIL PATRICK R.
Officer		 Purchase 32.7 240 672 7360 0 0.01 link
15.01.2025 17.01.2025 Baroldi Joseph
EVP, Chief Business Officer		 Purchase 31.43 77 318 2460 0 0 link
15.01.2025 17.01.2025 Baroldi Joseph
EVP, Chief Business Officer		 Purchase 31.43 276 175 8787 0 0.01 link
29.08.2024 03.09.2024 Geary Richard S
EVP, Chief Development Officer		 Sale 49.63 16 428 331 0 0 link
28.08.2024 03.09.2024 Geary Richard S
EVP, Chief Development Officer		 Sale 49.16 15 731 320 0 0 link
05.08.2024 05.08.2024 Geary Richard S
Executive Vice President, Chie		 Purchase 49.13 153 679 3128 0 0 link
17.01.2024 18.01.2024 O'NEIL PATRICK R.
EVP CLO & General Counsel		 Sale 50.42 390 452 7744 0 -0.01 link
17.01.2024 18.01.2024 Cadoret-Manier Onaiza
EVP, Chf GL Pdt Str & Oper Ofc		 Sale 50.42 280 537 5564 0 0 link
16.01.2024 18.01.2024 O'NEIL PATRICK R.
EVP CLO & General Counsel		 Purchase 50.65 1 045 470 20641 0 0.01 link
16.01.2024 18.01.2024 Cadoret-Manier Onaiza
EVP, Chf GL Pdt Str & Oper Ofc		 Purchase 50.65 762 890 15062 0 0.01 link
12.01.2024 17.01.2024 Schneider Eugene
EVP, Chf Clinical Develop Ofcr		 Sale 53.5 428 000 8000 0 -0.01 link
12.01.2024 17.01.2024 Schneider Eugene
EVP, Chf Clinical Develop Ofcr		 Purchase 32.6 260 800 8000 0 0.01 link
07.07.2023 11.07.2023 Monia Brett P
Chief Executive Officer		 Sale 42.25 787 963 18650 0 -0.01 link
17.10.2022 18.10.2022 Schneider Eugene
EVP, Chf Clinical Develop Ofcr		 Purchase 46.2 19 219 416 0 0 link
17.10.2022 18.10.2022 Hayden Michael R
Director		 Purchase 46.2 82 097 1777 0 0 link
08.09.2022 12.09.2022 Swayze Eric
EVP Research		 Sale 44.55 20 493 460 0 0 link
15.07.2022 19.07.2022 BERTHELSEN SPENCER R
Director		 Purchase 39.28 314 161 7998 0 0.01 link
15.07.2022 19.07.2022 Diaz Allene M.
Director		 Purchase 39.28 314 240 8000 0 0.01 link
15.07.2022 19.07.2022 Hayden Michael R
Director		 Purchase 39.28 279 281 7110 0 0.01 link
15.07.2022 19.07.2022 HERMAN JOAN E
Director		 Purchase 39.28 279 281 7110 0 0.01 link
15.07.2022 19.07.2022 KLEIN JOSEPH III
Director		 Sale 38.24 50 974 1333 0 0 link
15.07.2022 19.07.2022 KLEIN JOSEPH III
Director		 Purchase 39.28 314 161 7998 0 0.01 link
15.07.2022 19.07.2022 LOSCALZO JOSEPH
Director		 Purchase 39.28 314 161 7998 0 0.01 link
15.07.2022 19.07.2022 MUTO FREDERICK T
Director		 Purchase 39.28 314 161 7998 0 0.01 link
15.07.2022 19.07.2022 PARSHALL B LYNNE
Director		 Purchase 39.28 314 161 7998 0 0.01 link
15.07.2022 19.07.2022 WENDER JOSEPH H
Director		 Purchase 39.28 314 161 7998 0 0.01 link
02.12.2020 04.12.2020 Monia Brett P
Chief Executive Officer		 Sale 51.32 1 085 930 21160 0 -0.02 link
02.12.2020 04.12.2020 Monia Brett P
Chief Executive Officer		 Purchase 39.87 843 649 21160 0 0.02 link
02.12.2020 04.12.2020 BENNETT C FRANK
Chief Scientific Officer		 Sale 51.32 361 960 7053 0 -0.01 link
02.12.2020 04.12.2020 BENNETT C FRANK
Chief Scientific Officer		 Purchase 39.87 281 203 7053 0 0.01 link
25.11.2020 30.11.2020 PARSHALL B LYNNE
Director		 Sale 50.05 179 680 3590 0 0 link
25.11.2020 30.11.2020 PARSHALL B LYNNE
Director		 Purchase 39.87 143 133 3590 0 0 link
25.11.2020 30.11.2020 Geary Richard S
EVP, Development		 Sale 50.05 596 596 11920 0 -0.01 link
25.11.2020 30.11.2020 Geary Richard S
EVP, Development		 Purchase 39.87 475 250 11920 0 0.01 link
25.11.2020 30.11.2020 CROOKE STANLEY T
Exec Chairman of the Board		 Sale 50.05 650 150 12990 0 -0.01 link
25.11.2020 30.11.2020 CROOKE STANLEY T
Exec Chairman of the Board		 Purchase 39.87 517 911 12990 0 0.01 link
25.11.2020 30.11.2020 HOUGEN ELIZABETH L
EVP, Finance & CFO		 Sale 50.05 1 085 080 21680 0 -0.02 link
25.11.2020 30.11.2020 HOUGEN ELIZABETH L
EVP, Finance & CFO		 Purchase 39.87 864 382 21680 0 0.02 link

Institutions Volume Share, %
FMR, LLC 21520872 14.77
Vanguard Group Inc 14203481 9.74
T. Rowe Price Investment Management, Inc. 13201453 9.06
Blackrock Inc. 9057530 6.21
Bellevue Group AG 8713987 5.98
ClearBridge Investments, LLC 4707480 3.23
Wellington Management Group, LLP 4616978 3.17
Price (T.Rowe) Associates Inc 4255074 2.92
State Street Corporation 4008797 2.75
Pictet Asset Management Holding SA 3518317 2.41

ETF Share, % Profitability for 1 year, % Dividends, %
ARK Genomic Revolution ETF 4.28264 -8.08 0.05494
Direxion mRNA ETF 4.07 0
Franklin Genomic Advancements Fund Franklin Genomic Advancements Fund 2.10418 1.54 0.22433
Virtus LifeSci Biotech Products ETF 1.50588 36.79 0.13953
WisdomTree BioRevolution Fund 1.22724 -4.69 0.78691
ProShares UltraShort Nasdaq Biotechnology 1.02 -40.36 1.76
Future Tech ETF 0.61003 426.34 0.8416
Principal Healthcare Innovators ETF 0.61003 618.5 0.8416
Direxion Daily S&P Biotech Bull 3x Shares 0.60271 4067.92 0.25924
Invesco Nasdaq Biotechnology ETF 0.60137 28.58 0.8565
iShares MSCI USA Small-Cap Min Vol Factor ETF 0.59103 18.2 1.66828
First Trust Nasdaq Pharmaceuticals ETF 0.44459 18.37 2.19901
John Hancock Multifactor Small Cap ETF 0.42029 16.88 1.54912
iShares Exponential Technologies ETF 0.41549 5.87 1.22275
ProShares Ultra Nasdaq Biotechnology 0.4108 51.7 0.85651
First Trust Mid Cap Growth AlphaDEX Fund 0.36738 26.95 0.9035
Motley Fool Next Index ETF 0.3542 23.87 0.61129
RiverNorth Patriot ETF 0.34329 22.15 2.28129
Amplify Etho Climate Leadership U.S. ETF 0.33517 22.79 1.41942
iShares Morningstar Small-Cap Growth ETF 0.25021 587.89 0.72598
iShares Morningstar Small-Cap Growth ETF 0.25021 33.63 0.72598
iShares Russell Mid-Cap Growth ETF 0.22323 29.59 0.69551
Fidelity Growth Opportunities ETF 0.2118 32.75 0.48881
BNY Mellon US Mid Cap Core Equity ETF 0.19795 30.41 1.5641
First Trust Mid Cap Core AlphaDEX Fund 0.18442 18.49 1.65423
Schwab U.S. Small-Cap ETF 0.1589 17.47 1.51433
JPMorgan BetaBuilders U.S. Mid Cap Equity ETF 0.15392 21.79 1.42082
SoFi Next 500 ETF 0.14262 29.56 1.43041
Schwab US Mid-Cap ETF 0.13899 17.28 1.59098
iShares Morningstar Small-Cap ETF 0.12527 30.1 1.60498
iShares Morningstar Small-Cap ETF 0.12527 391.25 1.60498
First Trust Multi Cap Growth AlphaDEX Fund 0.11066 41.56 1.02425
iShares Russell 2500 ETF 0.10586 18.06 1.58987
Vanguard Extended Market ETF 0.1 24.2 1.34786
Invesco Russell 1000 Equal Weight ETF 0.08175 16.58 2.1901
SPDR S&P Kensho New Economies Composite ETF 0.08101 21.57 0.88486
Fidelity MSCI Health Care Index ETF 0.08038 3 1.46057
iShares Russell Midcap ETF 0.05747 20.77 1.71565
iShares ESG Aware MSCI USA Small-Cap ETF 0.05508 18.09 1.49366
Invesco FTSE RAFI US 1500 Small-Mid ETF 0.04666 17.58 1.75869
John Hancock Multifactor Mid Cap ETF 0.04032 20.65 1.52586
Humankind US Stock ETF 0.0328 18.81 1.99919
JPMorgan Carbon Transition U.S. Equity ETF 0.02452 25.53 1.26506
iShares Russell 1000 Growth ETF 0.02264 31.85 0.68889
Adasina Social Justice All Cap Global ETF 0.02044 16.32 2.09739
Vanguard ESG U.S. Stock ETF 0.02 23.54 1.26927
Vanguard Russell 1000 Growth ETF 0.02 31.62 0.68737
Avantis Responsible U.S. Equity ETF 0.01728 26.78 1.45257
FlexShares Morningstar US Market Factor Tilt Index Fund 0.01529 21.94 1.69572
iShares Dow Jones U.S. ETF 0.01218 25.05 1.41797
iShares Russell 3000 ETF 0.01212 24.83 1.43482
Schwab 1000 Index ETF 0.01162 25.15 1.42441
Goldman Sachs MarketBeta U.S. 1000 Equity ETF 0.01146 33 1.42661
Schwab U.S. Broad Market ETF 0.01125 24.86 1.43354
Columbia Research Enhanced Core ETF 0.0112 33.58 1.60295
Vanguard Russell 1000 ETF 0.01 25.16 1.43539
Vanguard Russell 3000 ETF 0.01 31.87 1.43817
Avantis U.S. Equity ETF 0.00608 23.04 1.59151
iShares Russell Mid-Cap Value ETF 0.00587 18.01 2.03934
iShares Russell 1000 Value ETF 0.00187 17.45 2.15361
Columbia Research Enhanced Value ETF 0.00155 28.02 2.60097
Dimensional U.S. Core Equity 2 ETF 0.00023 30.76 1.47098
Vanguard Russell 1000 Value ETF 0 17.7 2.15186



Head Job title Payment Year of birth
Mr. Darren Gonzales Chief Accounting Officer & Senior VP N/A
Dr. Brett P. Monia Ph.D. Founder, CEO & Director 1.71M 1961 (64 years)
Ms. B. Lynne Parshall Esq., J.D. Director 334.64k 1954 (71 year)
Dr. C. Frank Bennett BSc, Ph.D. Executive VP & Chief Scientific Officer 651.64k 1957 (68 years)
Mr. D. Wade Walke Ph.D. Senior Vice President of Investor Relations N/A
Ms. Elizabeth L. Hougen M.A., M.B.A., M.S. Executive VP of Finance & CFO 1.02M 1962 (63 years)
Dr. Richard S. Geary Ph.D. Executive VP & Chief Development Officer 946.26k 1958 (67 years)
Ms. Hayley Soffer Vice President of Corporate Communications N/A
Dr. Eric E. Swayze Ph.D. Executive Vice President of Research 1966 (59 years)
Mr. Patrick R. O'Neil Esq. Executive VP, Chief Legal Officer, General Counsel & Corporate Secretary 1974 (51 year)

Address: United States, Carlsbad, CA , 2855 Gazelle Court - open in Google maps, open in Yandex maps
Website: http://www.ionispharma.com