NASDAQ: VRTX - Vertex

Yield per half year: +6.1%
Sector: Healthcare

Share chart Vertex


About

Vertex Pharmaceuticals Incorporated занимается разработкой и коммерциализацией методов лечения муковисцидоза. Компания продает SYMDEKO / SYMKEVI, ORKAMBI и KALYDECO для лечения пациентов с муковисцидозом, у которых есть специфические мутации в гене трансмембранного регулятора муковисцидоза; и TRIKAFTA для лечения пациентов с CF в возрасте 12 лет и старше, у которых есть по меньшей мере одна мутация F508del в регуляторе трансмембранной проводимости муковисцидоза или гене CFTR.

More details
Его портфель включает в себя Pipeline for Alpha-1 antitrypsin дефицит, который находится в фазе 2 клинических испытаний; VX-864, второй исследуемый маломолекулярный корректор для лечения дефицита ААТ, который проходит фазу 1 клинических испытаний; и VX-147, который завершил Фазу 1 клинических испытаний по лечению APOL1-опосредованного фокального сегментарного гломерулосклероза, или ФСГС, и других серьезных заболеваний почек. Компания продает свою продукцию в основном специализированным аптекам и специализированным дистрибьюторам в США, а также специализированным дистрибьюторам и розничным сетям, а также больницам и клиникам по всему миру. Vertex Pharmaceuticals Incorporated сотрудничает с CRISPR Therapeutics AG; Арбор Биотехнологии, Инк .; Moderna, Inc .; Genomics plc; Merck KGaA; Дармштадт, Германия; X-Chem, Inc .; Janssen Pharmaceuticals, Inc.; Merck KGaA; Kymera Therapeutics; Ribometrix, Inc .; Molecular Templates, Inc .; и Affinia Therapeutics, а также о сотрудничестве в области стратегических исследований и лицензионном соглашении с Obsidian Therapeutics, Inc. для открытия новых методов лечения, которые регулируют редактирование генов для лечения серьезных заболеваний. Компания была основана в 1989 году, ее штаб-квартира находится в Бостоне, штат Массачусетс.


Main settings

Цена ао 416.03
P/E 48.28
P/S 13.65
P/BV 9.34
EV/EBITDA 37.24
Дивиденд ао
Див.доход ао
EBITDA 1.4579
Сайт http://www.vrtx.com
Число акций ао 0.2605 млрд
Выручка 4.16
ISIN US92532F1003
Change price per day: -0.9195% (400.23)
Change price per week: -2.49% (406.67)
Change price per month: -3.86% (412.45)
Change price per 3 month: -8.5% (433.4)
Change price per half year: +6.1% (373.74)
Change price per year: +21.96% (325.15)
Change price per 3 year: +98.54% (199.73)
Change price per 5 year: +36.15% (291.26)
Change price per year to date: -2.82% (408.05)


All parameters ⇨

Grade

Underestimation

Title Value Grade
P/S 13.65 1
P/BV 9.34 1
P/E 48.28 6
EV/EBITDA 37.24 5
Total:

Efficiency

Title Value Grade
ROA, % 17.71 5
ROE, % 22.99 7
Total:

Dividends

Title Value Grade
Div yield, % 0 1
DSI 0 0
Total:

Debt

Title Value Grade
Debt/EBITDA 0.2057 10
Total:

Growth impulse

Title Value Grade
Profit growth, % 117.21 10
Share price growth, % 71.08 10
Dividend growth, % 0 0
Total:

Insider trading

Transaction date Date of disclosure Insider Type Price Volume Quantity Share before, % Share after, % Document
05.04.2024 09.04.2024 Westphal Jeffrey
10% Owner
Sale 30.05 23 773 500 791133 0 -1.94 link
20.03.2024 20.03.2024 2020 IRREVOCABLE TRUST FOR BEN
13(D) GROUP MEMBER
Sale 30.04 328 217 10926 0 -0.03 link
20.03.2024 20.03.2024 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 30.04 327 947 10917 0 -0.03 link
20.03.2024 20.03.2024 ITEM SECOND IRR. TRUST FBO JAC
13(D) GROUP MEMBER
Sale 30.04 329 088 10955 0 -0.03 link
19.03.2024 20.03.2024 2020 IRREVOCABLE TRUST FOR BEN
13(D) GROUP MEMBER
Sale 30.06 930 477 30954 0 -0.08 link
19.03.2024 20.03.2024 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 30.05 929 777 30941 0 -0.08 link
19.03.2024 20.03.2024 ITEM SECOND IRR. TRUST FBO JAC
13(D) GROUP MEMBER
Sale 30.06 937 060 31173 0 -0.08 link
18.03.2024 20.03.2024 2020 IRREVOCABLE TRUST FOR BEN
13(D) GROUP MEMBER
Sale 30.05 208 968 6954 0 -0.02 link
18.03.2024 20.03.2024 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 30.05 207 646 6910 0 -0.02 link
18.03.2024 20.03.2024 ITEM SECOND IRR. TRUST FBO JAC
13(D) GROUP MEMBER
Sale 30.04 209 289 6967 0 -0.02 link
14.03.2024 14.03.2024 2020 IRREVOCABLE TRUST FOR BEN
13(D) GROUP MEMBER
Sale 30.01 256 826 8558 0 -0.02 link
13.03.2024 14.03.2024 2020 IRREVOCABLE TRUST FOR BEN
13(D) GROUP MEMBER
Sale 30 42 360 1412 0 0 link
12.12.2023 12.12.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 28.88 1 228 990 42555 0 -0.1 link
11.12.2023 12.12.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 28.73 2 034 720 70822 0 -0.17 link
08.12.2023 12.12.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 28.64 1 057 020 36907 0 -0.09 link
04.12.2023 04.12.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 27.82 525 798 18900 0 -0.05 link
01.12.2023 04.12.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 27.76 2 084 780 75100 0 -0.18 link
30.11.2023 04.12.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 27.98 2 333 530 83400 0 -0.2 link
14.09.2023 18.09.2023 DeStefano David
PRESIDENT & CEO
Buy 2.96 1 484 300 501453 0 1.23 link
14.07.2023 14.07.2023 Westphal Jeffery
10% Owner
Sale 18.66 1 665 140 89236 0 -0.22 link
13.07.2023 14.07.2023 Westphal Jeffery
10% Owner
Sale 18.91 2 933 810 155146 0 -0.38 link
12.07.2023 14.07.2023 Westphal Jeffery
10% Owner
Sale 18.9 1 527 420 80816 0 -0.2 link
30.06.2023 05.07.2023 Westphal Jeffery
10% Owner
Sale 19.08 11 615 900 608798 0 -1.49 link
28.06.2023 30.06.2023 Westphal Jeffery
10% Owner
Sale 18.26 14 608 000 800000 0 -1.96 link
21.04.2023 21.04.2023 Tensile Capital Management LP
10% Owner
Sale 22.32 97 829 4383 0 -0.01 link
20.04.2023 21.04.2023 Tensile Capital Management LP
10% Owner
Sale 22.35 1 225 790 54845 0 -0.13 link
19.04.2023 21.04.2023 Tensile Capital Management LP
10% Owner
Sale 22.61 1 001 920 44313 0 -0.11 link
04.04.2023 04.04.2023 ITEM SECOND IRR. TRUST FBO JAC
13(D) GROUP MEMBER
Sale 21.41 781 015 36479 0 -0.09 link
04.04.2023 04.04.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 21.41 781 037 36480 0 -0.09 link
03.04.2023 04.04.2023 ITEM SECOND IRR. TRUST FBO JAC
13(D) GROUP MEMBER
Sale 21.05 570 939 27123 0 -0.07 link
03.04.2023 04.04.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 21.05 570 939 27123 0 -0.07 link
31.03.2023 04.04.2023 ITEM SECOND IRR. TRUST FBO JAC
13(D) GROUP MEMBER
Sale 20.77 672 263 32367 0 -0.08 link
31.03.2023 04.04.2023 ITEM SECOND IRR. TRUST FBO ANN
13(D) GROUP MEMBER
Sale 20.77 672 263 32367 0 -0.08 link
16.03.2023 16.03.2023 Westphal Jeffery
10% Owner
Sale 17.75 24 409 200 1375164 0 -3.37 link
15.03.2023 16.03.2023 Westphal Jeffery
10% Owner
Sale 18.51 2 042 120 110325 0 -0.27 link
14.03.2023 16.03.2023 Westphal Jeffery
10% Owner
Sale 18.67 445 914 23884 0 -0.06 link
09.03.2023 10.03.2023 Westphal Jeffery
10% Owner
Sale 18.85 661 333 35084 0 -0.09 link
08.03.2023 10.03.2023 Westphal Jeffery
10% Owner
Sale 18.63 1 171 030 62857 0 -0.15 link
30.09.2022 30.09.2022 DeStefano David
President & CEO
Sale 13.94 402 866 28900 0 -0.07 link
29.09.2022 30.09.2022 DeStefano David
President & CEO
Sale 13.5 458 055 33930 0 -0.08 link
28.09.2022 30.09.2022 DeStefano David
President & CEO
Sale 13.59 494 934 36419 0 -0.09 link
28.01.2022 31.01.2022 DeStefano David
PRESIDENT & CEO
Buy 0.15 1 050 7000 0 0.03 link

Main owners

Institutions Volume Share, %
Vanguard Group Inc 22282180 8.62
Blackrock Inc. 21881203 8.47
Capital World Investors 21805770 8.44
FMR, LLC 12979511 5.02
State Street Corporation 12083818 4.68
AllianceBernstein L.P. 7039738 2.72
Price (T.Rowe) Associates Inc 5887412 2.28
Geode Capital Management, LLC 5673419 2.2
JP Morgan Chase & Company 5624265 2.18
Wellington Management Group, LLP 5228538 2.02

Contained in ETF

ETF Share, % Profitability for 1 year, % Dividends, %
WisdomTree BioRevolution Fund 2.45
Apex Healthcare ETF 4.13
iShares Evolved U.S. Innovative Healthcare ETF 5.23 27.98 2.79
Direxion mRNA ETF 6.6
WisdomTree U.S. Growth & Momentum Fund 1.94
Fidelity Women's Leadership ETF 1.89 0.92
Invesco S&P 500® Equal Weight Health Care ETF 1.73 32.90 0.64
Future Health ETF 2.9
JPMorgan Social Advancement ETF 2.27 0.47
FinEx USA UCITS ETF 0.26 54.54
БПИФ Первая Америк. акции 0
FinEx RUB GLOBAL EQUITY UC ETF 0.06 48.06
FinEx USD GLOBAL EQUITY UC ETF 0.06 37.73
Invesco S&P 500 GARP ETF 1.74 50.83 1.30
Franklin Systematic Style Premia ETF Franklin Liberty Systematic Style Premia Fund 0.65 -1.72 1.08
Vanguard Health Care ETF 1.77 29.53 1.32
iShares Biotechnology ETF 7.94 31.10 0.30
iShares MSCI Global Min Vol Factor ETF 1.08 17.63 2.33
VanEck Biotech ETF 9.4 38.53 0.44
Invesco Biotechnology & Genome ETF 4.83 37.15 0.06
Natixis Loomis Sayles Focused Growth ETF 4.63 0.03
ClearBridge All Cap Growth ESG ETF 2.98 26.89 0.31
ProShares Ultra Nasdaq Biotechnology 5.82 57.51 0.15
ROBO Global Healthcare Technology and Innovation ETF 1.69 43.56
Tema Obesity & Cardiometabolic ETF 5.23
ETC 6 Meridian Quality Growth ETF 2.99 0.02
Invesco Nasdaq Biotechnology ETF 7.96 0.85
First Trust Nasdaq Pharmaceuticals ETF 3.5 10.11 1.43
iShares ESG MSCI USA Min Vol Factor ETF 1.56 1.69
Tema Neuroscience and Mental Health ETF 4.6
Franklin Genomic Advancements Fund Franklin Genomic Advancements Fund 4.52 61.17

Similar companies



Company management

Head Job title Payment Year of birth
Mr. Charles F. Wagner Jr. Executive VP & CFO 2.06M 1968 (56 years)
Mr. Mike Tirozzi SVP and Chief Information & Data Officer N/A
Mr. Stuart A. Arbuckle B.Sc. Executive VP & COO 2.7M 1966 (58 years)
Dr. David M. Altshuler M.D., Ph.D. Executive VP & Chief Scientific Officer 2.03M 1965 (59 years)
Dr. Jeffrey Marc Leiden M.D., Ph.D. Executive Chairman 92.93k 1956 (68 years)
Susie Lisa Senior Vice President of Investor Relations N/A
Mr. Jonathan Biller J.D. Executive VP & Chief Legal Officer N/A 1964 (60 years)
Ms. Nina Devlin Senior VP & Chief Communications Officer N/A
Ms. Stephanie Franklin Senior VP & Chief Human Resources Officer N/A
Mr. Amit K. Sachdev J.D. Executive VP & Chief Patient and External Affairs Officer 1.41M 1968 (56 years)

About company

Address: United States, Boston, MA , 50 Northern Avenue - open in Google maps, open in Yandex maps
Website: http://www.vrtx.com
Phone: +617 341 6100